Better understand the concentration levels and ecotoxicity of pharmaceuticals
Develop low environmental footprint manufacturing processes while increasing resilience
Reduce the overall environmental footprint of pharmaceuticals, throughout their lifecycle
However, it is critical that we fully understand and mitigate the environmental impact resulting from their production, use and disposal.
The project aims to offer information regarding occurrence of pharmaceuticals in the environment, their persistence, environmental fate, and toxicity (via in-vitro & in-vivo models) as well as application of in-silico methods to provide information about the basic risk management and fate prediction in the environment.
It also aims to develop a set of technologies that enable greener and overall more efficient pharmaceuticals production.
Develop spectroscopic sensors that allow measuring pharmaceutical micropollutants in wastewater and the natural environment, and perform monitoring campaigns to better understand their environmental impact
Perform in-vitro and in-vivo ecotoxicity studies of core compounds used in the industry, in order to gain better understanding of the environmental impact of currently unregulated chemical compounds.
Develop in-silico tools for the design of non-toxic pharmaceuticals (Green-by-design), based on current literature and the outcomes of the monitoring campaigns & ecotoxicity studies
Develop a digital transformation toolset towards efficient Continuous Biomanufacturing for robust/resilient pro- cesses, and to also reduce the use of carcinogenic substances produced with current methods (batch production)
Develop a polarimetric sensor for surface inspection, allowing more efficient rinsing in production and reduction in the use of chemicals
Develop a laser-based sensor for inline liquids analysis, able to detect trace amounts of chemicals and impurities
